Most of the diseases have been cured by drugs that have been initially tested on animals and then tried on humans. Mouse is a commonly used guinea pig for such experiments and there has been a constant investigation going on various diseases across the globe. One such disease is Alzheimer’s disease. Some of the investigations conducted on mice revealed that the reaction of Alzeheimer’s disease can be retarded to a certain level using the testosterone therapy. According to the Journal of Neuroscience the application of testosterone-based hormone therapy will be extremely useful in declining the bad effects of Alzeheimer’s disease that happens in elder people.
In one such recent study under the able guidance of Christian Spike from the USC, the effectiveness of the testosterone theory was checked in mice. As it is known that the Alzheimer’s disease can be common in people with less testosterone being produced in their body. The researcher also believed that appropriate quantity of testosterone production in a human body can help to prevent the occurrence of Alzheimer’s in humans.
The experiments were conducted in such a way that they can help to understand the role of testosterone. Initially the mice were treated in such a way that they loose the ability of testosterone production and then only a few from the group were injected with a sample of the drug. On the other hand the other mice were not treated with such a drug to ensure that they act as a control for the experiment.
Then once the observations were made it was analyzed that high quantity of protein beta-amyloid was found in mice from which the testosterone was removed and it is commonly known that this protein is a major cause for Alzheimer’s disease, this also led to behavioral changes and undesired characteristics. However when the mice which were injected with the drug did not show any such changes or characters. All these inferences point towards the fact that these experiments might be able to yield something substantial in the field of disease treatment. The researchers are now planning to observe the effect of this hormone over a longer duration of time so that they can probably utilize it in elderly males.
There has been a lot of research that has also shown the positive effects of testosterone in various other fields in the treatment involving neurology. The group of people researching at the USC was also of the opinion that testosterone also had an impact on the muscle co-ordination of the mice that were tested.